Living cells are sustained by countless chemical reactions that must be carefully regulated to maintain internal order and ...

A team has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational ...

The ensemble-function approach provides a quantitative catalytic model for serine proteases and identifies repeatedly evolved catalytic strategies. Credit: Science (2025). DOI: 10.1126/science.ado5068 ...

Small-scale interactions of substrates with an enzyme's active site — over distances smaller than the length of a chemical bond — can make big differences to the enzyme's catalytic efficiency. Any ...

Enzymes catalyze the critical chemical reactions that help build and power living organisms. But chemists studying the origin of life on Earth face a vexing question: How did these metabolic reactions ...

A pair of enzymes from the human gut microbiome can convert type A red blood cells to type O red blood cells. These enzymes might, with further development, help make universal blood that could be ...

Osaka, Japan – When your wounds heal and your liver detoxifies a poison such as histamine you ingested, you can thank the class of enzymes known as copper amine oxidases for their assistance.

Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life – how enzymes are ...