Researchers have built the first cross-tissue single-cell atlas of T cell and B cell receptor repertoires in healthy piglets, revealing biased V(D)J gene usage, conserved CDR3 structures, and ...

Prostate cancer has long frustrated immunologists. Checkpoint inhibitors that unleash the immune system against tumors in the skin, lung, and bladder have largely fallen short in the prostate, in part ...

An interdisciplinary team of scientists has developed a technology to decode immune cell communication. By measuring interactions between cells, the method offers insights into how the human body ...

More than 35,000 men in the United States die from prostate cancer each year. Now, a new study reveals the immune cell weaponry we might use to save lives. Researchers have discovered that the immune ...

While birthday candles measure the number of years someone has lived, they don't always tell the full story about someone's health. Two people born on the same day can have immune systems that age ...

In a study of historic scale, scientists have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation ...

A first-of-its-kind comprehensive map of the network of connections in the human immune system has uncovered previously unknown interactions and filled in gaps in understanding why approved ...

A map of the immune cell landscape found in the bone marrow of patients with multiple myeloma could shed light on how the immune system interacts with cancerous plasma cells. It could also help ...

The immune system depends on molecular alarms that detect danger inside cells. One of these alarms is STING, short for "stimulator of interferon genes". STING helps cells respond to infections, ...

Researchers have mapped how the immune response in people with sepsis changes over time. The work, led by King’s College London, could help to pave the way for treatments that target the specific ...

A study shows that the ratio of two white blood cell types can predict unhealthy aging. In older adults, a greater proportion of certain cells foretold chronic disease and death a decade later. The ...