One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

In diagrams and illustrations of cells, DNA is sometimes shown as a mass in the cell's nucleus, like a bowl of ramen noodles. For many years, it's been standard practice to take images of cells that ...

Researchers at the CNIO show that oestrogens regulate gene expression by changing DNA supercoiling. Hormone-activated ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact within these droplet-like structures. The findings connect molecular ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...

Left: staining for H3K27me3, which marks inactive DNA, on a nucleus of a wildtype embryo consisting of two cells Right: staining for H3K27me3, which marks inactive DNA, on a nucleus of an embryo ...

Researchers have identified how the architecture of the cell nucleus can change gene activity in plants. This discovery reveals fundamental knowledge about genome regulation and points towards future ...

In an era where the U.S. healthcare system spends $4.5T annually yet faces systemic failures, with life expectancy plummeting to a three-decade low and chronic disease rates at an all-time high, the ...