Vaccinations have revolutionized healthcare, but designing them remains complex, requiring time and creativity, especially for vaccines against viruses, which are difficult to study. “Each virus ...
Hosted on MSN
Massively parallel profiling reveals thousands of hidden viral proteins and conserved mechanisms
In the study, "Pan-viral ORFs discovery using massively parallel ribosome profiling," published in Science, researchers developed MPRP to identify translated regions by profiling synthetic viral ...
The RNA profiling core provides access to expertise and infrastructure for advanced transcriptomic profiling approaches, including Ribosome Profiling (mapping of translating ribosomes), CLIP (mapping ...
With the help of a technique called Massively Parallel Ribosome Profiling (MPRP), Shira Weingarten-Gabbay and colleagues identified more than 4000 open reading frames (ORFs) across 679 ...
This study illustrates how persistent mRNA rG4 structures induce ribosome pausing and collisions, leading to proteostasis collapse in senescent cells. The RNA helicase DHX9 acts as a key regulator, ...
Research identifies ribosome biogenesis factor MYBBP1A as a driver of acute myeloid leukaemia growth, highlighting a ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results