Proteoforms, the diverse molecular variants of proteins, are key to understanding cellular functions, disease mechanisms, and ...

A therapeutic strategy based on alternative splicing of the MECP2 gene could restore protein levels in Rett syndrome, a neurological disorder caused by mutations in that gene. Scientists at Baylor ...

Biology textbooks explain that cells follow a universal rule when processing gene transcripts to make proteins. Non-coding ...

CRF awards four global grants to advance CHM research toward new clinical trial endpoints and therapeutic approaches—driving progress toward treatments.

When closely related species mate, their offspring sometimes survive but cannot reproduce. This pattern often affects males first, with hybrid males frequently failing to produce functional sperm even ...

A new gene-targeting strategy that boosts a crucial brain protein could pave the way for the first effective treatment for ...

Ongoing; DT-818 (DM1) Dosing in Patients Expected in the First Half of 2026 Cash and Securities of $219.8 Million as of Year-End Supports Ongoing Clinical Execution CARLSBAD, Calif., March 09, 2026 ...

Dyne has aligned with the U.S. Food and Drug Administration (FDA) on the HARMONIA Phase 3 trial design and protocol. HARMONIA is intended to serve as a confirmatory trial to support conversion of ...

When Associate Professor Eliezer Calo PhD '11 was applying for faculty positions, he was drawn to MIT not only because it's ...

We have City Hunter coming up soon, but before that we have another artifact from the past, the Game Boy Advance RPG Wizman's ...

Over the past decade, however, a wave of technological advances has begun to expand the druggable proteome. These include covalent inhibitors (such as sotorasib), chemical proteomics, and AI-enabled ...

Houston Methodist scientists have uncovered an unexpected side of a protein best known for its link to brain diseases. The ...